Does MITOXANTRONE Cause Pancytopenia? 148 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 148 reports of Pancytopenia have been filed in association with MITOXANTRONE (mitoXANTRONE). This represents 3.6% of all adverse event reports for MITOXANTRONE.
148
Reports of Pancytopenia with MITOXANTRONE
3.6%
of all MITOXANTRONE reports
24
Deaths
57
Hospitalizations
How Dangerous Is Pancytopenia From MITOXANTRONE?
Of the 148 reports, 24 (16.2%) resulted in death, 57 (38.5%) required hospitalization, and 29 (19.6%) were considered life-threatening.
Is Pancytopenia Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for MITOXANTRONE. However, 148 reports have been filed with the FAERS database.
What Other Side Effects Does MITOXANTRONE Cause?
Febrile neutropenia (668)
Off label use (368)
Neutropenia (296)
Drug ineffective (293)
Thrombocytopenia (256)
Sepsis (240)
Pyrexia (214)
Product use in unapproved indication (177)
Disease progression (173)
Acute myeloid leukaemia (167)
What Other Drugs Cause Pancytopenia?
METHOTREXATE (5,377)
CYCLOPHOSPHAMIDE (3,351)
CARBOPLATIN (2,910)
RITUXIMAB (2,400)
LENALIDOMIDE (2,259)
DOXORUBICIN (2,212)
VINCRISTINE (2,180)
ETOPOSIDE (2,129)
DEXAMETHASONE (2,053)
PREDNISONE (1,743)
Which MITOXANTRONE Alternatives Have Lower Pancytopenia Risk?
MITOXANTRONE vs MITRAGYNINE\HERBALS
MITOXANTRONE vs MIZORIBINE
MITOXANTRONE vs MOBOCERTINIB
MITOXANTRONE vs MOCLOBEMIDE
MITOXANTRONE vs MODAFINIL