MITOXANTRONE for Progressive multiple sclerosis: Side Effects & Safety Data
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There are 6 adverse event reports in the FDA FAERS database where MITOXANTRONE was used for Progressive multiple sclerosis.
Most Reported Side Effects for MITOXANTRONE
| Side Effect | Reports | % | Deaths | Hosp. |
|---|---|---|---|---|
| Febrile neutropenia | 668 | 16.0% | 87 | 403 |
| Off label use | 368 | 8.8% | 82 | 142 |
| Neutropenia | 296 | 7.1% | 76 | 144 |
| Drug ineffective | 293 | 7.0% | 79 | 119 |
| Thrombocytopenia | 256 | 6.1% | 66 | 128 |
| Sepsis | 240 | 5.8% | 94 | 98 |
| Pyrexia | 214 | 5.1% | 46 | 125 |
| Product use in unapproved indication | 177 | 4.3% | 53 | 58 |
| Disease progression | 173 | 4.2% | 58 | 42 |
| Acute myeloid leukaemia | 167 | 4.0% | 78 | 43 |
| Pneumonia | 157 | 3.8% | 76 | 71 |
| Infection | 153 | 3.7% | 72 | 37 |
| Pancytopenia | 148 | 3.6% | 24 | 57 |
| Myelodysplastic syndrome | 139 | 3.3% | 35 | 25 |
| Septic shock | 133 | 3.2% | 57 | 98 |
Other Indications for MITOXANTRONE
Acute myeloid leukaemia (1,248)
Acute lymphocytic leukaemia (414)
Diffuse large b-cell lymphoma (201)
Product used for unknown indication (183)
Acute promyelocytic leukaemia (158)
B-cell lymphoma (125)
Multiple sclerosis (112)
Non-hodgkin's lymphoma (104)
B-cell type acute leukaemia (101)
Acute lymphocytic leukaemia recurrent (89)
Other Drugs Used for Progressive multiple sclerosis
OCRELIZUMAB (400)
RITUXIMAB (40)
DALFAMPRIDINE (26)
GLATIRAMER (21)
FINGOLIMOD (20)
SIPONIMOD (20)
INTERFERON BETA-1A (19)
DIMETHYL (18)
OFATUMUMAB (18)
NATALIZUMAB (14)