Does MITOXANTRONE Cause Second primary malignancy? 95 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 95 reports of Second primary malignancy have been filed in association with MITOXANTRONE (mitoXANTRONE). This represents 2.3% of all adverse event reports for MITOXANTRONE.
95
Reports of Second primary malignancy with MITOXANTRONE
2.3%
of all MITOXANTRONE reports
43
Deaths
5
Hospitalizations
How Dangerous Is Second primary malignancy From MITOXANTRONE?
Of the 95 reports, 43 (45.3%) resulted in death, 5 (5.3%) required hospitalization, and 7 (7.4%) were considered life-threatening.
Is Second primary malignancy Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for MITOXANTRONE. However, 95 reports have been filed with the FAERS database.
What Other Side Effects Does MITOXANTRONE Cause?
Febrile neutropenia (668)
Off label use (368)
Neutropenia (296)
Drug ineffective (293)
Thrombocytopenia (256)
Sepsis (240)
Pyrexia (214)
Product use in unapproved indication (177)
Disease progression (173)
Acute myeloid leukaemia (167)
What Other Drugs Cause Second primary malignancy?
CYCLOPHOSPHAMIDE (1,247)
DOXORUBICIN (1,151)
VINCRISTINE (908)
IMATINIB (763)
PALBOCICLIB (658)
RITUXIMAB (646)
RUXOLITINIB (611)
ETOPOSIDE (573)
PREDNISONE (517)
OCTREOTIDE (496)
Which MITOXANTRONE Alternatives Have Lower Second primary malignancy Risk?
MITOXANTRONE vs MITRAGYNINE\HERBALS
MITOXANTRONE vs MIZORIBINE
MITOXANTRONE vs MOBOCERTINIB
MITOXANTRONE vs MOCLOBEMIDE
MITOXANTRONE vs MODAFINIL