Does NALMEFENE Cause Coma? 47 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 47 reports of Coma have been filed in association with NALMEFENE (Zurnai). This represents 23.9% of all adverse event reports for NALMEFENE.
47
Reports of Coma with NALMEFENE
23.9%
of all NALMEFENE reports
36
Deaths
31
Hospitalizations
How Dangerous Is Coma From NALMEFENE?
Of the 47 reports, 36 (76.6%) resulted in death, 31 (66.0%) required hospitalization, and 8 (17.0%) were considered life-threatening.
Is Coma Listed in the Official Label?
Yes, Coma is listed as a known adverse reaction in the official FDA drug label for NALMEFENE.
What Other Side Effects Does NALMEFENE Cause?
Drug ineffective (66)
Toxicity to various agents (43)
Hypotension (30)
Respiratory depression (25)
Depressed level of consciousness (19)
Hepatotoxicity (18)
Acute kidney injury (15)
Drug withdrawal syndrome (15)
Metabolic acidosis (14)
Off label use (14)
What Other Drugs Cause Coma?
ACETAMINOPHEN (2,386)
QUETIAPINE (2,267)
DIAZEPAM (2,250)
ALPRAZOLAM (2,042)
PREGABALIN (1,941)
TRAMADOL (1,708)
ZOPICLONE (1,405)
VENLAFAXINE (1,342)
OXAZEPAM (1,256)
BACLOFEN (1,133)
Which NALMEFENE Alternatives Have Lower Coma Risk?
NALMEFENE vs NALOXEGOL OXALATE
NALMEFENE vs NALOXONE
NALMEFENE vs NALOXONE\OXYCODONE
NALMEFENE vs NALOXONE\TILIDINE
NALMEFENE vs NALTREXONE