Does NIRAPARIB Cause Constipation? 4,128 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 4,128 reports of Constipation have been filed in association with NIRAPARIB (ZEJULA). This represents 19.1% of all adverse event reports for NIRAPARIB.
4,128
Reports of Constipation with NIRAPARIB
19.1%
of all NIRAPARIB reports
108
Deaths
984
Hospitalizations
How Dangerous Is Constipation From NIRAPARIB?
Of the 4,128 reports, 108 (2.6%) resulted in death, 984 (23.8%) required hospitalization, and 138 (3.3%) were considered life-threatening.
Is Constipation Listed in the Official Label?
Yes, Constipation is listed as a known adverse reaction in the official FDA drug label for NIRAPARIB.
What Other Side Effects Does NIRAPARIB Cause?
Nausea (5,794)
Fatigue (5,240)
Platelet count decreased (4,102)
Insomnia (2,861)
Blood pressure increased (2,464)
Headache (2,383)
Off label use (2,213)
Vomiting (2,029)
Carbohydrate antigen 125 increased (1,868)
Decreased appetite (1,865)
What Other Drugs Cause Constipation?
LENALIDOMIDE (9,635)
ADALIMUMAB (4,063)
SEMAGLUTIDE (4,036)
TIRZEPATIDE (3,417)
ERENUMAB-AOOE (3,104)
MORPHINE (2,979)
OXYCODONE (2,747)
PALBOCICLIB (2,705)
POMALIDOMIDE (2,374)
ACETAMINOPHEN (2,346)
Which NIRAPARIB Alternatives Have Lower Constipation Risk?
NIRAPARIB vs NIRMATRELVIR\RITONAVIR
NIRAPARIB vs NIROGACESTAT
NIRAPARIB vs NIROGACESTAT HYDROBROMIDE
NIRAPARIB vs NIRSEVIMAB
NIRAPARIB vs NIRSEVIMAB-ALIP