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Important: This site presents data from the FDA Adverse Event Reporting System (FAERS). A report does not mean the drug caused the event. Full disclaimer.

Constipation: Which Medications Cause It? (161,987 Reports Across 2,017 Drugs)

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Constipation has been reported as an adverse event with 2,017 different drugs in the FDA's FAERS database, with 161,987 total reports. 7,459 of these reports resulted in death.The drugs most commonly associated with Constipation are LENALIDOMIDE, NIRAPARIB, and ADALIMUMAB.

161,987
Total Reports
2,017
Drugs Involved
7,459
Deaths
41,364
Hospitalizations
60.9 yrs
Average Patient Age
63.0% / 37.0%
Female / Male

Which Drugs Cause Constipation Most Often?

Drug Reports % of Drug Reports Deaths Hosp. Life-Threat.
LENALIDOMIDE 9,635 2.8% 183 1,395 74
NIRAPARIB 4,128 19.1% 108 984 138
ADALIMUMAB 4,063 0.8% 155 1,662 21
SEMAGLUTIDE 4,036 6.8% 14 937 48
TIRZEPATIDE 3,417 3.4% 6 341 20
ERENUMAB-AOOE 3,104 6.2% 2 174 15
MORPHINE 2,979 2.5% 387 1,620 150
OXYCODONE 2,747 1.4% 324 923 62
PALBOCICLIB 2,705 3.0% 119 508 16
POMALIDOMIDE 2,374 2.6% 52 334 18
ACETAMINOPHEN 2,346 1.7% 431 1,115 203
PATIROMER 2,120 16.2% 37 202 1
CABOZANTINIB S-MALATE 2,098 5.3% 91 359 9
SEVELAMER 2,041 35.7% 1 32 7
DEXAMETHASONE 2,010 1.6% 286 892 112
HYDROMORPHONE 1,983 2.4% 451 815 163
LEVOTHYROXINE 1,936 3.1% 23 862 92
VEDOLIZUMAB 1,894 2.6% 18 672 6
NINTEDANIB 1,756 6.7% 144 803 54
RITUXIMAB 1,750 1.0% 305 508 46

View all 2,017 drugs →

Top 3 Drugs Associated With Constipation

9,635 reports
4,128 reports
4,063 reports

Related Side Effects

Drug ineffective (1,049,718) Off label use (762,782) Death (660,423) Fatigue (599,248) Nausea (562,301) Diarrhoea (491,550) Pain (471,975) Headache (460,069) Dyspnoea (409,496) Dizziness (352,922)