Does NIRAPARIB Cause Hyperchlorhydria? 13 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 13 reports of Hyperchlorhydria have been filed in association with NIRAPARIB (ZEJULA). This represents 0.1% of all adverse event reports for NIRAPARIB.
13
Reports of Hyperchlorhydria with NIRAPARIB
0.1%
of all NIRAPARIB reports
1
Deaths
4
Hospitalizations
How Dangerous Is Hyperchlorhydria From NIRAPARIB?
Of the 13 reports, 1 (7.7%) resulted in death, 4 (30.8%) required hospitalization.
Is Hyperchlorhydria Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for NIRAPARIB. However, 13 reports have been filed with the FAERS database.
What Other Side Effects Does NIRAPARIB Cause?
Nausea (5,794)
Fatigue (5,240)
Constipation (4,128)
Platelet count decreased (4,102)
Insomnia (2,861)
Blood pressure increased (2,464)
Headache (2,383)
Off label use (2,213)
Vomiting (2,029)
Carbohydrate antigen 125 increased (1,868)
What Other Drugs Cause Hyperchlorhydria?
OMEPRAZOLE (2,571)
LANSOPRAZOLE (1,983)
ESOMEPRAZOLE (1,734)
PANTOPRAZOLE (1,139)
DEXLANSOPRAZOLE (751)
DIMETHYL (51)
DULAGLUTIDE (48)
PALBOCICLIB (42)
RANITIDINE (38)
ADALIMUMAB (36)
Which NIRAPARIB Alternatives Have Lower Hyperchlorhydria Risk?
NIRAPARIB vs NIRMATRELVIR\RITONAVIR
NIRAPARIB vs NIROGACESTAT
NIRAPARIB vs NIROGACESTAT HYDROBROMIDE
NIRAPARIB vs NIRSEVIMAB
NIRAPARIB vs NIRSEVIMAB-ALIP