OBINUTUZUMAB for Prophylaxis: Side Effects & Safety Data
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There are 8 adverse event reports in the FDA FAERS database where OBINUTUZUMAB was used for Prophylaxis.
Most Reported Side Effects for OBINUTUZUMAB
| Side Effect | Reports | % | Deaths | Hosp. |
|---|---|---|---|---|
| Off label use | 1,584 | 11.2% | 139 | 239 |
| Neutropenia | 1,276 | 9.0% | 112 | 331 |
| Febrile neutropenia | 955 | 6.7% | 91 | 473 |
| Covid-19 | 942 | 6.6% | 263 | 505 |
| Pyrexia | 920 | 6.5% | 122 | 525 |
| Thrombocytopenia | 889 | 6.3% | 77 | 164 |
| Disease progression | 831 | 5.9% | 184 | 75 |
| Infusion related reaction | 789 | 5.6% | 58 | 252 |
| Pneumonia | 662 | 4.7% | 170 | 445 |
| Anaemia | 640 | 4.5% | 53 | 111 |
| Atrial fibrillation | 548 | 3.9% | 36 | 141 |
| Infection | 517 | 3.6% | 69 | 94 |
| Chills | 483 | 3.4% | 15 | 158 |
| Dyspnoea | 478 | 3.4% | 59 | 187 |
| Nausea | 470 | 3.3% | 37 | 166 |
Other Indications for OBINUTUZUMAB
Chronic lymphocytic leukaemia (4,557)
Follicular lymphoma (2,527)
Product used for unknown indication (1,743)
B-cell lymphoma (1,200)
Diffuse large b-cell lymphoma (1,193)
Mantle cell lymphoma (441)
Non-hodgkin's lymphoma (387)
Lymphoma (238)
Marginal zone lymphoma (188)
Chemotherapy (135)
Other Drugs Used for Prophylaxis
PEGFILGRASTIM (7,424)
HUMAN C1-ESTERASE INHIBITOR (5,950)
DENOSUMAB (4,541)
SULFAMETHOXAZOLE\TRIMETHOPRIM (3,197)
ASPIRIN (2,083)
VALACYCLOVIR (1,574)
PANTOPRAZOLE (1,502)
VARICELLA-ZOSTER VIRUS STRAIN OKA/MERCK LIVE ANTIGEN (1,444)
CLOPIDOGREL BISULFATE (1,296)
ENOXAPARIN (1,278)