OLARATUMAB: 565 Adverse Event Reports & Safety Profile
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565
Total FAERS Reports
109 (19.3%)
Deaths Reported
169
Hospitalizations
565
As Primary/Secondary Suspect
99
Life-Threatening
2
Disabilities
Prescription
Status
FDA Application: 761038 ·
First Report: 200811 · Latest Report: 20240228
What Are the Most Common OLARATUMAB Side Effects?
#1 Most Reported
Off label use
124 reports (21.9%)
#2 Most Reported
Neutropenia
66 reports (11.7%)
#3 Most Reported
Infusion related reaction
64 reports (11.3%)
All OLARATUMAB Side Effects by Frequency
| Side Effect | Reports | % of Total | Deaths | Hosp. |
|---|---|---|---|---|
| Off label use | 124 | 22.0% | 32 | 29 |
| Neutropenia | 66 | 11.7% | 2 | 11 |
| Infusion related reaction | 64 | 11.3% | 2 | 25 |
| Febrile neutropenia | 57 | 10.1% | 6 | 36 |
| Drug ineffective | 49 | 8.7% | 10 | 12 |
| Death | 44 | 7.8% | 44 | 3 |
| Malignant neoplasm progression | 43 | 7.6% | 10 | 8 |
| Product use in unapproved indication | 40 | 7.1% | 7 | 14 |
| Disease progression | 33 | 5.8% | 10 | 5 |
| Anaphylactic reaction | 29 | 5.1% | 0 | 13 |
| Dyspnoea | 27 | 4.8% | 4 | 12 |
| Diarrhoea | 21 | 3.7% | 2 | 11 |
| Fatigue | 20 | 3.5% | 1 | 2 |
| Nausea | 19 | 3.4% | 1 | 5 |
| Neoplasm recurrence | 19 | 3.4% | 1 | 0 |
| Anaemia | 18 | 3.2% | 1 | 5 |
| Neoplasm progression | 18 | 3.2% | 4 | 0 |
| Hypotension | 17 | 3.0% | 0 | 10 |
| Mucosal inflammation | 14 | 2.5% | 0 | 7 |
| Cardiac arrest | 13 | 2.3% | 1 | 11 |
Who Reports OLARATUMAB Side Effects? Age & Gender Data
Gender: 48.3% female, 51.7% male. Average age: 55.6 years. Most reports from: US. View detailed demographics →
Is OLARATUMAB Getting Safer? Reports by Year
| Year | Reports | Deaths | Hosp. |
|---|---|---|---|
| 2008 | 1 | 1 | 0 |
| 2015 | 1 | 0 | 1 |
| 2016 | 28 | 6 | 11 |
| 2017 | 65 | 10 | 22 |
| 2018 | 103 | 10 | 69 |
| 2019 | 10 | 4 | 5 |
| 2020 | 1 | 1 | 0 |
| 2024 | 1 | 1 | 0 |
What Is OLARATUMAB Used For?
| Indication | Reports |
|---|---|
| Soft tissue sarcoma | 156 |
| Product used for unknown indication | 146 |
| Leiomyosarcoma | 33 |
| Undifferentiated sarcoma | 27 |
| Sarcoma | 26 |
| Sarcoma metastatic | 21 |
| Uterine leiomyosarcoma | 14 |
| Leiomyosarcoma metastatic | 13 |
| Endometrial stromal sarcoma | 12 |
| Non-small cell lung cancer | 11 |
OLARATUMAB vs Alternatives: Which Is Safer?
OLARATUMAB vs OLECLUMAB
OLARATUMAB vs OLIVE OIL\SOYBEAN OIL
OLARATUMAB vs OLMESARTAN
OLARATUMAB vs OLMESARTAN MEDOXOMIL
OLARATUMAB vs OLMETEC
OLARATUMAB vs OLODATEROL
OLARATUMAB vs OLODATEROL\TIOTROPIUM
OLARATUMAB vs OLOPATADINE
OLARATUMAB vs OLUTASIDENIB
OLARATUMAB vs OMACETAXINE MEPESUCCINATE
Official FDA Label for OLARATUMAB
Official prescribing information from the FDA-approved drug label.