OLARATUMAB for Leiomyosarcoma: Side Effects & Safety Data
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There are 33 adverse event reports in the FDA FAERS database where OLARATUMAB was used for Leiomyosarcoma.
Most Reported Side Effects for OLARATUMAB
| Side Effect | Reports | % | Deaths | Hosp. |
|---|---|---|---|---|
| Off label use | 124 | 22.0% | 32 | 29 |
| Neutropenia | 66 | 11.7% | 2 | 11 |
| Infusion related reaction | 64 | 11.3% | 2 | 25 |
| Febrile neutropenia | 57 | 10.1% | 6 | 36 |
| Drug ineffective | 49 | 8.7% | 10 | 12 |
| Death | 44 | 7.8% | 44 | 3 |
| Malignant neoplasm progression | 43 | 7.6% | 10 | 8 |
| Product use in unapproved indication | 40 | 7.1% | 7 | 14 |
| Disease progression | 33 | 5.8% | 10 | 5 |
| Anaphylactic reaction | 29 | 5.1% | 0 | 13 |
| Dyspnoea | 27 | 4.8% | 4 | 12 |
| Diarrhoea | 21 | 3.7% | 2 | 11 |
| Fatigue | 20 | 3.5% | 1 | 2 |
| Nausea | 19 | 3.4% | 1 | 5 |
| Neoplasm recurrence | 19 | 3.4% | 1 | 0 |
Other Indications for OLARATUMAB
Soft tissue sarcoma (156)
Product used for unknown indication (146)
Undifferentiated sarcoma (27)
Sarcoma (26)
Sarcoma metastatic (21)
Uterine leiomyosarcoma (14)
Leiomyosarcoma metastatic (13)
Endometrial stromal sarcoma (12)
Non-small cell lung cancer (11)
Liposarcoma (10)
Other Drugs Used for Leiomyosarcoma
DOXORUBICIN (185)
TRABECTEDIN (142)
PAZOPANIB (132)
GEMCITABINE (99)
DOCETAXEL (89)
IFOSFAMIDE (57)
ERIBULIN (50)
NIVOLUMAB (44)
DACARBAZINE (42)
GEMCITABINE\GEMCITABINE (42)