OSILODROSTAT for Cushing's syndrome: Side Effects & Safety Data
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There are 626 adverse event reports in the FDA FAERS database where OSILODROSTAT was used for Cushing's syndrome.
Most Reported Side Effects for OSILODROSTAT
| Side Effect | Reports | % | Deaths | Hosp. |
|---|---|---|---|---|
| Off label use | 272 | 16.7% | 30 | 93 |
| Fatigue | 249 | 15.3% | 10 | 62 |
| Nausea | 204 | 12.6% | 8 | 52 |
| Headache | 111 | 6.8% | 2 | 24 |
| Adrenal insufficiency | 97 | 6.0% | 8 | 39 |
| Death | 97 | 6.0% | 97 | 21 |
| Asthenia | 92 | 5.7% | 5 | 47 |
| Dizziness | 91 | 5.6% | 5 | 24 |
| Decreased appetite | 90 | 5.5% | 8 | 38 |
| Diarrhoea | 90 | 5.5% | 0 | 34 |
| Vomiting | 82 | 5.0% | 3 | 38 |
| Cortisol decreased | 70 | 4.3% | 1 | 32 |
| Arthralgia | 65 | 4.0% | 0 | 14 |
| Covid-19 | 64 | 3.9% | 8 | 23 |
| Product dose omission issue | 49 | 3.0% | 0 | 25 |
Other Indications for OSILODROSTAT
Pituitary-dependent cushing's syndrome (669)
Product used for unknown indication (282)
Off label use (52)
Ectopic acth syndrome (40)
Hyperadrenocorticism (23)
Adrenal gland cancer (17)
Cortisol increased (14)
Adrenocortical carcinoma (11)
Pituitary tumour benign (8)
Other Drugs Used for Cushing's syndrome
MIFEPRISTONE (2,136)
LEVOKETOCONAZOLE (201)
METYRAPONE (177)
PASIREOTIDE (119)
KETOCONAZOLE (118)
PASIREOTIDE DIASPARTATE (32)
HYDROCORTISONE (30)
KORLYM (30)
SPIRONOLACTONE (24)
MITOTANE (22)