OSILODROSTAT for Off label use: Side Effects & Safety Data
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There are 52 adverse event reports in the FDA FAERS database where OSILODROSTAT was used for Off label use.
Most Reported Side Effects for OSILODROSTAT
| Side Effect | Reports | % | Deaths | Hosp. |
|---|---|---|---|---|
| Off label use | 272 | 16.7% | 30 | 93 |
| Fatigue | 249 | 15.3% | 10 | 62 |
| Nausea | 204 | 12.6% | 8 | 52 |
| Headache | 111 | 6.8% | 2 | 24 |
| Adrenal insufficiency | 97 | 6.0% | 8 | 39 |
| Death | 97 | 6.0% | 97 | 21 |
| Asthenia | 92 | 5.7% | 5 | 47 |
| Dizziness | 91 | 5.6% | 5 | 24 |
| Decreased appetite | 90 | 5.5% | 8 | 38 |
| Diarrhoea | 90 | 5.5% | 0 | 34 |
| Vomiting | 82 | 5.0% | 3 | 38 |
| Cortisol decreased | 70 | 4.3% | 1 | 32 |
| Arthralgia | 65 | 4.0% | 0 | 14 |
| Covid-19 | 64 | 3.9% | 8 | 23 |
| Product dose omission issue | 49 | 3.0% | 0 | 25 |
Other Indications for OSILODROSTAT
Pituitary-dependent cushing's syndrome (669)
Cushing's syndrome (626)
Product used for unknown indication (282)
Ectopic acth syndrome (40)
Hyperadrenocorticism (23)
Adrenal gland cancer (17)
Cortisol increased (14)
Adrenocortical carcinoma (11)
Pituitary tumour benign (8)
Other Drugs Used for Off label use
LENALIDOMIDE (5,767)
ECULIZUMAB (3,550)
CERTOLIZUMAB PEGOL (2,256)
ABOBOTULINUMTOXINA (2,170)
LEVETIRACETAM (2,161)
APREMILAST (1,995)
PROPRANOLOL (1,576)
CETIRIZINE (1,416)
HUMAN IMMUNOGLOBULIN G (1,129)
THALIDOMIDE (1,033)