Does PACLITAXEL Cause Hypopituitarism? 64 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 64 reports of Hypopituitarism have been filed in association with PACLITAXEL (PACLITAXEL PACLITAXEL). This represents 0.1% of all adverse event reports for PACLITAXEL.
64
Reports of Hypopituitarism with PACLITAXEL
0.1%
of all PACLITAXEL reports
4
Deaths
46
Hospitalizations
How Dangerous Is Hypopituitarism From PACLITAXEL?
Of the 64 reports, 4 (6.3%) resulted in death, 46 (71.9%) required hospitalization, and 12 (18.8%) were considered life-threatening.
Is Hypopituitarism Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for PACLITAXEL. However, 64 reports have been filed with the FAERS database.
What Other Side Effects Does PACLITAXEL Cause?
Neutropenia (4,553)
Nausea (4,521)
Dyspnoea (4,519)
Diarrhoea (4,289)
Off label use (4,075)
Anaemia (3,949)
Neuropathy peripheral (3,508)
Malignant neoplasm progression (3,484)
Fatigue (3,418)
Death (3,143)
What Other Drugs Cause Hypopituitarism?
NIVOLUMAB (455)
IPILIMUMAB (391)
PEMBROLIZUMAB (203)
CARBOPLATIN (89)
ATEZOLIZUMAB (71)
SOMATROPIN (67)
BEVACIZUMAB (45)
PREDNISONE (41)
DURVALUMAB (38)
LENVATINIB (34)
Which PACLITAXEL Alternatives Have Lower Hypopituitarism Risk?
PACLITAXEL vs PACRITINIB
PACLITAXEL vs PALBOCICLIB
PACLITAXEL vs PALIPERIDONE
PACLITAXEL vs PALIVIZUMAB
PACLITAXEL vs PALONOSETRON