Hypopituitarism: Which Medications Cause It? (1,436 Reports Across 95 Drugs)
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Hypopituitarism has been reported as an adverse event with 95 different drugs in the FDA's FAERS database, with 1,436 total reports. 139 of these reports resulted in death.The drugs most commonly associated with Hypopituitarism are NIVOLUMAB, IPILIMUMAB, and PEMBROLIZUMAB.
1,436
Total Reports
95
Drugs Involved
139
Deaths
833
Hospitalizations
58.3 yrs
Average Patient Age
40.6% / 59.4%
Female / Male
Which Drugs Cause Hypopituitarism Most Often?
| Drug | Reports | % of Drug Reports | Deaths | Hosp. | Life-Threat. |
|---|---|---|---|---|---|
| NIVOLUMAB | 455 | 0.5% | 66 | 343 | 48 |
| IPILIMUMAB | 391 | 1.1% | 45 | 278 | 32 |
| PEMBROLIZUMAB | 203 | 0.2% | 22 | 134 | 25 |
| CARBOPLATIN | 89 | 0.1% | 6 | 56 | 13 |
| ATEZOLIZUMAB | 71 | 0.2% | 7 | 47 | 3 |
| SOMATROPIN | 67 | 0.1% | 3 | 20 | 0 |
| PACLITAXEL | 64 | 0.1% | 4 | 46 | 12 |
| BEVACIZUMAB | 45 | 0.1% | 4 | 26 | 0 |
| PREDNISONE | 41 | 0.0% | 1 | 8 | 0 |
| DURVALUMAB | 38 | 0.2% | 8 | 16 | 5 |
| LENVATINIB | 34 | 0.1% | 1 | 21 | 0 |
| PEMETREXED | 33 | 0.1% | 3 | 26 | 5 |
| CYCLOPHOSPHAMIDE | 30 | 0.0% | 1 | 17 | 5 |
| CISPLATIN | 25 | 0.1% | 2 | 16 | 4 |
| HYDROCORTISONE | 25 | 0.1% | 4 | 6 | 3 |
| EPOPROSTENOL | 22 | 0.2% | 0 | 17 | 1 |
| OMALIZUMAB | 21 | 0.0% | 0 | 1 | 0 |
| DUPILUMAB | 20 | 0.0% | 0 | 2 | 0 |
| LEVOTHYROXINE | 19 | 0.0% | 0 | 6 | 1 |
| CABOZANTINIB S-MALATE | 18 | 0.1% | 2 | 10 | 6 |