Does PACLITAXEL Cause Immune-mediated hypophysitis? 42 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 42 reports of Immune-mediated hypophysitis have been filed in association with PACLITAXEL (PACLITAXEL PACLITAXEL). This represents 0.1% of all adverse event reports for PACLITAXEL.
42
Reports of Immune-mediated hypophysitis with PACLITAXEL
0.1%
of all PACLITAXEL reports
0
Deaths
19
Hospitalizations
How Dangerous Is Immune-mediated hypophysitis From PACLITAXEL?
Of the 42 reports, 19 (45.2%) required hospitalization, and 8 (19.0%) were considered life-threatening.
Is Immune-mediated hypophysitis Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for PACLITAXEL. However, 42 reports have been filed with the FAERS database.
What Other Side Effects Does PACLITAXEL Cause?
Neutropenia (4,553)
Nausea (4,521)
Dyspnoea (4,519)
Diarrhoea (4,289)
Off label use (4,075)
Anaemia (3,949)
Neuropathy peripheral (3,508)
Malignant neoplasm progression (3,484)
Fatigue (3,418)
Death (3,143)
What Other Drugs Cause Immune-mediated hypophysitis?
NIVOLUMAB (171)
PEMBROLIZUMAB (137)
IPILIMUMAB (135)
CARBOPLATIN (59)
CYCLOPHOSPHAMIDE (33)
EPIRUBICIN (23)
DURVALUMAB (14)
BEVACIZUMAB (12)
DOXORUBICIN (11)
LENVATINIB (10)
Which PACLITAXEL Alternatives Have Lower Immune-mediated hypophysitis Risk?
PACLITAXEL vs PACRITINIB
PACLITAXEL vs PALBOCICLIB
PACLITAXEL vs PALIPERIDONE
PACLITAXEL vs PALIVIZUMAB
PACLITAXEL vs PALONOSETRON