Does PANOBINOSTAT Cause Pancytopenia? 37 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 37 reports of Pancytopenia have been filed in association with PANOBINOSTAT. This represents 2.0% of all adverse event reports for PANOBINOSTAT.
37
Reports of Pancytopenia with PANOBINOSTAT
2.0%
of all PANOBINOSTAT reports
23
Deaths
23
Hospitalizations
How Dangerous Is Pancytopenia From PANOBINOSTAT?
Of the 37 reports, 23 (62.2%) resulted in death, 23 (62.2%) required hospitalization, and 17 (45.9%) were considered life-threatening.
Is Pancytopenia Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for PANOBINOSTAT. However, 37 reports have been filed with the FAERS database.
What Other Side Effects Does PANOBINOSTAT Cause?
Diarrhoea (368)
Plasma cell myeloma (279)
Platelet count decreased (192)
Death (190)
Malignant neoplasm progression (166)
Fatigue (162)
Nausea (154)
Thrombocytopenia (141)
Off label use (112)
Vomiting (109)
What Other Drugs Cause Pancytopenia?
METHOTREXATE (5,377)
CYCLOPHOSPHAMIDE (3,351)
CARBOPLATIN (2,910)
RITUXIMAB (2,400)
LENALIDOMIDE (2,259)
DOXORUBICIN (2,212)
VINCRISTINE (2,180)
ETOPOSIDE (2,129)
DEXAMETHASONE (2,053)
PREDNISONE (1,743)
Which PANOBINOSTAT Alternatives Have Lower Pancytopenia Risk?
PANOBINOSTAT vs PANTOPRAZOLE
PANOBINOSTAT vs PANTOPRAZOLE ANHYDROUS
PANOBINOSTAT vs PANTOTHENIC ACID
PANOBINOSTAT vs PAPAVERINE
PANOBINOSTAT vs PARACETAMOL