Does PEGLOTICASE Cause Cardiac failure? 8 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 8 reports of Cardiac failure have been filed in association with PEGLOTICASE (Krystexxa). This represents 0.3% of all adverse event reports for PEGLOTICASE.
8
Reports of Cardiac failure with PEGLOTICASE
0.3%
of all PEGLOTICASE reports
2
Deaths
5
Hospitalizations
How Dangerous Is Cardiac failure From PEGLOTICASE?
Of the 8 reports, 2 (25.0%) resulted in death, 5 (62.5%) required hospitalization, and 2 (25.0%) were considered life-threatening.
Is Cardiac failure Listed in the Official Label?
Yes, Cardiac failure is listed as a known adverse reaction in the official FDA drug label for PEGLOTICASE.
What Other Side Effects Does PEGLOTICASE Cause?
Gout (487)
Blood uric acid increased (359)
Infusion related reaction (284)
Therapeutic response decreased (186)
Dyspnoea (153)
Urticaria (133)
Drug ineffective (131)
Nausea (119)
Pruritus (118)
Rash (116)
What Other Drugs Cause Cardiac failure?
SACUBITRIL\VALSARTAN (4,504)
FUROSEMIDE (1,841)
APIXABAN (1,575)
CYCLOPHOSPHAMIDE (1,514)
DOXORUBICIN (1,367)
ADALIMUMAB (1,278)
DEXAMETHASONE (1,271)
TREPROSTINIL (1,168)
BISOPROLOL (1,159)
LENALIDOMIDE (1,115)
Which PEGLOTICASE Alternatives Have Lower Cardiac failure Risk?
PEGLOTICASE vs PEGUNIGALSIDASE ALFA-IWXJ
PEGLOTICASE vs PEGVALIASE-PQPZ
PEGLOTICASE vs PEGVISOMANT
PEGLOTICASE vs PEGZEREPOETIN ALFA
PEGLOTICASE vs PEMBROLIZUMAB