PEMBROLIZUMAB for Diffuse large b-cell lymphoma: Side Effects & Safety Data
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There are 107 adverse event reports in the FDA FAERS database where PEMBROLIZUMAB was used for Diffuse large b-cell lymphoma.
Most Reported Side Effects for PEMBROLIZUMAB
| Side Effect | Reports | % | Deaths | Hosp. |
|---|---|---|---|---|
| Malignant neoplasm progression | 10,111 | 12.1% | 5,124 | 3,426 |
| Death | 4,744 | 5.7% | 4,737 | 893 |
| Diarrhoea | 4,251 | 5.1% | 556 | 2,141 |
| Fatigue | 3,833 | 4.6% | 365 | 1,246 |
| Off label use | 3,416 | 4.1% | 747 | 1,045 |
| Product use in unapproved indication | 3,191 | 3.8% | 514 | 909 |
| Pyrexia | 3,155 | 3.8% | 444 | 2,194 |
| Rash | 2,900 | 3.5% | 289 | 1,047 |
| Nausea | 2,670 | 3.2% | 335 | 1,237 |
| Decreased appetite | 2,486 | 3.0% | 371 | 1,235 |
| Hypothyroidism | 2,326 | 2.8% | 242 | 935 |
| Product use issue | 2,323 | 2.8% | 417 | 610 |
| Hypertension | 2,245 | 2.7% | 276 | 1,118 |
| Asthenia | 2,131 | 2.5% | 300 | 1,058 |
| Interstitial lung disease | 2,113 | 2.5% | 869 | 1,276 |
Other Indications for PEMBROLIZUMAB
Non-small cell lung cancer (6,893)
Triple negative breast cancer (5,148)
Endometrial cancer (4,343)
Lung adenocarcinoma (3,954)
Lung neoplasm malignant (3,575)
Malignant melanoma (3,261)
Renal cell carcinoma (3,027)
Metastatic malignant melanoma (2,742)
Uterine cancer (2,223)
Product used for unknown indication (2,091)
Other Drugs Used for Diffuse large b-cell lymphoma
RITUXIMAB (22,275)
CYCLOPHOSPHAMIDE (16,598)
DOXORUBICIN (15,213)
VINCRISTINE (14,922)
PREDNISONE (11,266)
LENALIDOMIDE (7,858)
ETOPOSIDE (4,698)
PREDNISOLONE (4,086)
CYTARABINE (3,857)
DEXAMETHASONE (3,696)