Does PEMBROLIZUMAB Cause Hypothyroidism? 2,326 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 2,326 reports of Hypothyroidism have been filed in association with PEMBROLIZUMAB (KEYTRUDA). This represents 2.8% of all adverse event reports for PEMBROLIZUMAB.
2,326
Reports of Hypothyroidism with PEMBROLIZUMAB
2.8%
of all PEMBROLIZUMAB reports
242
Deaths
935
Hospitalizations
How Dangerous Is Hypothyroidism From PEMBROLIZUMAB?
Of the 2,326 reports, 242 (10.4%) resulted in death, 935 (40.2%) required hospitalization, and 124 (5.3%) were considered life-threatening.
Is Hypothyroidism Listed in the Official Label?
Yes, Hypothyroidism is listed as a known adverse reaction in the official FDA drug label for PEMBROLIZUMAB.
What Other Side Effects Does PEMBROLIZUMAB Cause?
Malignant neoplasm progression (10,111)
Death (4,744)
Diarrhoea (4,251)
Fatigue (3,833)
Off label use (3,416)
Product use in unapproved indication (3,191)
Pyrexia (3,155)
Rash (2,900)
Nausea (2,670)
Decreased appetite (2,486)
What Other Drugs Cause Hypothyroidism?
LEVOTHYROXINE (2,107)
NIVOLUMAB (1,939)
LENVATINIB (1,375)
ATEZOLIZUMAB (881)
ALBUTEROL (877)
CARBOPLATIN (830)
IPILIMUMAB (770)
AMIODARONE (764)
PREDNISONE (739)
CABOZANTINIB S-MALATE (724)
Which PEMBROLIZUMAB Alternatives Have Lower Hypothyroidism Risk?
PEMBROLIZUMAB vs PEMETREXED
PEMBROLIZUMAB vs PEMIGATINIB
PEMBROLIZUMAB vs PENICILLAMINE
PEMBROLIZUMAB vs PENICILLIN
PEMBROLIZUMAB vs PENICILLIN G