Hypothyroidism: Which Medications Cause It? (22,295 Reports Across 860 Drugs)
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Hypothyroidism has been reported as an adverse event with 860 different drugs in the FDA's FAERS database, with 22,295 total reports. 1,644 of these reports resulted in death.The drugs most commonly associated with Hypothyroidism are PEMBROLIZUMAB, LEVOTHYROXINE, and NIVOLUMAB.
22,295
Total Reports
860
Drugs Involved
1,644
Deaths
7,691
Hospitalizations
58.2 yrs
Average Patient Age
66.2% / 33.8%
Female / Male
Which Drugs Cause Hypothyroidism Most Often?
| Drug | Reports | % of Drug Reports | Deaths | Hosp. | Life-Threat. |
|---|---|---|---|---|---|
| PEMBROLIZUMAB | 2,326 | 2.8% | 242 | 935 | 124 |
| LEVOTHYROXINE | 2,107 | 3.4% | 115 | 656 | 184 |
| NIVOLUMAB | 1,939 | 2.2% | 267 | 946 | 178 |
| LENVATINIB | 1,375 | 4.1% | 165 | 698 | 46 |
| ATEZOLIZUMAB | 881 | 2.6% | 114 | 202 | 22 |
| ALBUTEROL | 877 | 0.9% | 60 | 461 | 165 |
| CARBOPLATIN | 830 | 1.0% | 74 | 237 | 35 |
| IPILIMUMAB | 770 | 2.1% | 83 | 453 | 74 |
| AMIODARONE | 764 | 3.0% | 38 | 415 | 114 |
| PREDNISONE | 739 | 0.5% | 62 | 387 | 176 |
| CABOZANTINIB S-MALATE | 724 | 1.8% | 49 | 128 | 16 |
| ADALIMUMAB | 592 | 0.1% | 12 | 160 | 5 |
| ALENDRONATE | 575 | 2.1% | 73 | 507 | 142 |
| BEVACIZUMAB | 569 | 0.7% | 102 | 131 | 20 |
| PACLITAXEL | 543 | 0.7% | 39 | 171 | 28 |
| BUDESONIDE | 542 | 2.2% | 58 | 283 | 169 |
| BUDESONIDE\FORMOTEROL | 531 | 1.5% | 36 | 258 | 62 |
| MONTELUKAST | 526 | 2.0% | 49 | 305 | 132 |
| APIXABAN | 517 | 0.3% | 81 | 407 | 152 |
| METHOTREXATE | 503 | 0.2% | 6 | 68 | 33 |