Does PEMBROLIZUMAB Cause Adrenal insufficiency? 1,270 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 1,270 reports of Adrenal insufficiency have been filed in association with PEMBROLIZUMAB (KEYTRUDA). This represents 1.5% of all adverse event reports for PEMBROLIZUMAB.
1,270
Reports of Adrenal insufficiency with PEMBROLIZUMAB
1.5%
of all PEMBROLIZUMAB reports
102
Deaths
716
Hospitalizations
How Dangerous Is Adrenal insufficiency From PEMBROLIZUMAB?
Of the 1,270 reports, 102 (8.0%) resulted in death, 716 (56.4%) required hospitalization, and 92 (7.2%) were considered life-threatening.
Is Adrenal insufficiency Listed in the Official Label?
Yes, Adrenal insufficiency is listed as a known adverse reaction in the official FDA drug label for PEMBROLIZUMAB.
What Other Side Effects Does PEMBROLIZUMAB Cause?
Malignant neoplasm progression (10,111)
Death (4,744)
Diarrhoea (4,251)
Fatigue (3,833)
Off label use (3,416)
Product use in unapproved indication (3,191)
Pyrexia (3,155)
Rash (2,900)
Nausea (2,670)
Decreased appetite (2,486)
What Other Drugs Cause Adrenal insufficiency?
NIVOLUMAB (1,285)
PREDNISONE (1,105)
IPILIMUMAB (851)
METHOTREXATE (644)
ADALIMUMAB (554)
ETANERCEPT (546)
TOCILIZUMAB (541)
HYDROXYCHLOROQUINE (517)
INFLIXIMAB (509)
ABATACEPT (489)
Which PEMBROLIZUMAB Alternatives Have Lower Adrenal insufficiency Risk?
PEMBROLIZUMAB vs PEMETREXED
PEMBROLIZUMAB vs PEMIGATINIB
PEMBROLIZUMAB vs PENICILLAMINE
PEMBROLIZUMAB vs PENICILLIN
PEMBROLIZUMAB vs PENICILLIN G