Adrenal insufficiency: Which Medications Cause It? (9,299 Reports Across 505 Drugs)
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Adrenal insufficiency has been reported as an adverse event with 505 different drugs in the FDA's FAERS database, with 9,299 total reports. 638 of these reports resulted in death.The drugs most commonly associated with Adrenal insufficiency are NIVOLUMAB, PEMBROLIZUMAB, and PREDNISONE.
9,299
Total Reports
505
Drugs Involved
638
Deaths
5,075
Hospitalizations
54.5 yrs
Average Patient Age
52.6% / 47.4%
Female / Male
Which Drugs Cause Adrenal insufficiency Most Often?
| Drug | Reports | % of Drug Reports | Deaths | Hosp. | Life-Threat. |
|---|---|---|---|---|---|
| NIVOLUMAB | 1,285 | 1.5% | 148 | 861 | 175 |
| PEMBROLIZUMAB | 1,270 | 1.5% | 102 | 716 | 92 |
| PREDNISONE | 1,105 | 0.7% | 47 | 767 | 157 |
| IPILIMUMAB | 851 | 2.3% | 87 | 579 | 95 |
| METHOTREXATE | 644 | 0.3% | 56 | 552 | 124 |
| ADALIMUMAB | 554 | 0.1% | 20 | 499 | 98 |
| ETANERCEPT | 546 | 0.2% | 18 | 411 | 100 |
| TOCILIZUMAB | 541 | 0.6% | 20 | 474 | 106 |
| HYDROXYCHLOROQUINE | 517 | 0.8% | 18 | 489 | 94 |
| INFLIXIMAB | 509 | 0.4% | 20 | 478 | 94 |
| ABATACEPT | 489 | 0.4% | 16 | 464 | 97 |
| LENVATINIB | 489 | 1.5% | 11 | 218 | 10 |
| ATEZOLIZUMAB | 478 | 1.4% | 57 | 202 | 19 |
| ANAKINRA | 466 | 3.8% | 19 | 452 | 93 |
| TRIAMCINOLONE | 459 | 6.9% | 22 | 385 | 82 |
| RITUXIMAB | 451 | 0.3% | 46 | 265 | 62 |
| SULFASALAZINE | 450 | 1.1% | 17 | 437 | 90 |
| NAPROXEN | 441 | 0.8% | 16 | 419 | 102 |
| DEXAMETHASONE | 440 | 0.4% | 48 | 211 | 73 |
| HYDROCORTISONE | 439 | 1.8% | 38 | 234 | 56 |