Does SULFASALAZINE Cause Adrenal insufficiency? 450 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 450 reports of Adrenal insufficiency have been filed in association with SULFASALAZINE (Azulfidine EN-tabs). This represents 1.1% of all adverse event reports for SULFASALAZINE.
450
Reports of Adrenal insufficiency with SULFASALAZINE
1.1%
of all SULFASALAZINE reports
17
Deaths
437
Hospitalizations
How Dangerous Is Adrenal insufficiency From SULFASALAZINE?
Of the 450 reports, 17 (3.8%) resulted in death, 437 (97.1%) required hospitalization, and 90 (20.0%) were considered life-threatening.
Is Adrenal insufficiency Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for SULFASALAZINE. However, 450 reports have been filed with the FAERS database.
What Other Side Effects Does SULFASALAZINE Cause?
Drug ineffective (22,365)
Rheumatoid arthritis (15,136)
Drug intolerance (11,530)
Pain (11,309)
Fatigue (9,684)
Joint swelling (9,673)
Rash (8,739)
Contraindicated product administered (8,698)
Arthralgia (8,527)
Abdominal discomfort (8,404)
What Other Drugs Cause Adrenal insufficiency?
NIVOLUMAB (1,285)
PEMBROLIZUMAB (1,270)
PREDNISONE (1,105)
IPILIMUMAB (851)
METHOTREXATE (644)
ADALIMUMAB (554)
ETANERCEPT (546)
TOCILIZUMAB (541)
HYDROXYCHLOROQUINE (517)
INFLIXIMAB (509)
Which SULFASALAZINE Alternatives Have Lower Adrenal insufficiency Risk?
SULFASALAZINE vs SULFATHIAZOLE
SULFASALAZINE vs SULFISOMIDINE
SULFASALAZINE vs SULFUR
SULFASALAZINE vs SULFUR HEXAFLUORIDE
SULFASALAZINE vs SULINDAC