Does PEMBROLIZUMAB Cause Brain oedema? 134 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 134 reports of Brain oedema have been filed in association with PEMBROLIZUMAB (KEYTRUDA). This represents 0.2% of all adverse event reports for PEMBROLIZUMAB.
134
Reports of Brain oedema with PEMBROLIZUMAB
0.2%
of all PEMBROLIZUMAB reports
25
Deaths
75
Hospitalizations
How Dangerous Is Brain oedema From PEMBROLIZUMAB?
Of the 134 reports, 25 (18.7%) resulted in death, 75 (56.0%) required hospitalization, and 11 (8.2%) were considered life-threatening.
Is Brain oedema Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for PEMBROLIZUMAB. However, 134 reports have been filed with the FAERS database.
What Other Side Effects Does PEMBROLIZUMAB Cause?
Malignant neoplasm progression (10,111)
Death (4,744)
Diarrhoea (4,251)
Fatigue (3,833)
Off label use (3,416)
Product use in unapproved indication (3,191)
Pyrexia (3,155)
Rash (2,900)
Nausea (2,670)
Decreased appetite (2,486)
What Other Drugs Cause Brain oedema?
ACETAMINOPHEN (407)
DEXAMETHASONE (254)
TACROLIMUS (232)
FENTANYL (222)
PREDNISONE (205)
METHOTREXATE (200)
OXYCODONE (191)
CYCLOPHOSPHAMIDE (188)
METHYLPREDNISOLONE (188)
METHADONE (187)
Which PEMBROLIZUMAB Alternatives Have Lower Brain oedema Risk?
PEMBROLIZUMAB vs PEMETREXED
PEMBROLIZUMAB vs PEMIGATINIB
PEMBROLIZUMAB vs PENICILLAMINE
PEMBROLIZUMAB vs PENICILLIN
PEMBROLIZUMAB vs PENICILLIN G