Does METHOTREXATE Cause Brain oedema? 200 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 200 reports of Brain oedema have been filed in association with METHOTREXATE (Methotrexate). This represents 0.1% of all adverse event reports for METHOTREXATE.
200
Reports of Brain oedema with METHOTREXATE
0.1%
of all METHOTREXATE reports
85
Deaths
153
Hospitalizations
How Dangerous Is Brain oedema From METHOTREXATE?
Of the 200 reports, 85 (42.5%) resulted in death, 153 (76.5%) required hospitalization, and 58 (29.0%) were considered life-threatening.
Is Brain oedema Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for METHOTREXATE. However, 200 reports have been filed with the FAERS database.
What Other Side Effects Does METHOTREXATE Cause?
Drug ineffective (70,142)
Rheumatoid arthritis (29,254)
Off label use (24,020)
Pain (23,773)
Drug intolerance (22,555)
Arthralgia (21,831)
Fatigue (19,885)
Nausea (18,715)
Joint swelling (17,657)
Drug hypersensitivity (16,677)
What Other Drugs Cause Brain oedema?
ACETAMINOPHEN (407)
DEXAMETHASONE (254)
TACROLIMUS (232)
FENTANYL (222)
PREDNISONE (205)
OXYCODONE (191)
CYCLOPHOSPHAMIDE (188)
METHYLPREDNISOLONE (188)
METHADONE (187)
NIVOLUMAB (186)
Which METHOTREXATE Alternatives Have Lower Brain oedema Risk?
METHOTREXATE vs METHOXSALEN
METHOTREXATE vs METHOXY POLYETHYLENE GLYCOL-EPOETIN BETA
METHOTREXATE vs METHYL ALCOHOL
METHOTREXATE vs METHYLCOBALAMIN
METHOTREXATE vs METHYLDOPA