Does PEMBROLIZUMAB Cause Cardiomegaly? 31 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 31 reports of Cardiomegaly have been filed in association with PEMBROLIZUMAB (KEYTRUDA). This represents 0.0% of all adverse event reports for PEMBROLIZUMAB.
31
Reports of Cardiomegaly with PEMBROLIZUMAB
0.0%
of all PEMBROLIZUMAB reports
13
Deaths
21
Hospitalizations
How Dangerous Is Cardiomegaly From PEMBROLIZUMAB?
Of the 31 reports, 13 (41.9%) resulted in death, 21 (67.7%) required hospitalization, and 8 (25.8%) were considered life-threatening.
Is Cardiomegaly Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for PEMBROLIZUMAB. However, 31 reports have been filed with the FAERS database.
What Other Side Effects Does PEMBROLIZUMAB Cause?
Malignant neoplasm progression (10,111)
Death (4,744)
Diarrhoea (4,251)
Fatigue (3,833)
Off label use (3,416)
Product use in unapproved indication (3,191)
Pyrexia (3,155)
Rash (2,900)
Nausea (2,670)
Decreased appetite (2,486)
What Other Drugs Cause Cardiomegaly?
SACUBITRIL\VALSARTAN (365)
ADALIMUMAB (301)
ONDANSETRON (198)
OXYCODONE (164)
AMLODIPINE (161)
CARVEDILOL (151)
MACITENTAN (141)
ACETAMINOPHEN (133)
TREPROSTINIL (129)
FUROSEMIDE (122)
Which PEMBROLIZUMAB Alternatives Have Lower Cardiomegaly Risk?
PEMBROLIZUMAB vs PEMETREXED
PEMBROLIZUMAB vs PEMIGATINIB
PEMBROLIZUMAB vs PENICILLAMINE
PEMBROLIZUMAB vs PENICILLIN
PEMBROLIZUMAB vs PENICILLIN G