Does PEMBROLIZUMAB Cause Central hypothyroidism? 16 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 16 reports of Central hypothyroidism have been filed in association with PEMBROLIZUMAB (KEYTRUDA). This represents 0.0% of all adverse event reports for PEMBROLIZUMAB.
16
Reports of Central hypothyroidism with PEMBROLIZUMAB
0.0%
of all PEMBROLIZUMAB reports
0
Deaths
7
Hospitalizations
How Dangerous Is Central hypothyroidism From PEMBROLIZUMAB?
Of the 16 reports, 7 (43.8%) required hospitalization, and 1 (6.3%) were considered life-threatening.
Is Central hypothyroidism Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for PEMBROLIZUMAB. However, 16 reports have been filed with the FAERS database.
What Other Side Effects Does PEMBROLIZUMAB Cause?
Malignant neoplasm progression (10,111)
Death (4,744)
Diarrhoea (4,251)
Fatigue (3,833)
Off label use (3,416)
Product use in unapproved indication (3,191)
Pyrexia (3,155)
Rash (2,900)
Nausea (2,670)
Decreased appetite (2,486)
What Other Drugs Cause Central hypothyroidism?
DOXORUBICIN (77)
CYCLOPHOSPHAMIDE (75)
VINCRISTINE (72)
CYTARABINE (54)
PREDNISOLONE (47)
METHOTREXATE (44)
ASPARAGINASE (42)
DEXAMETHASONE (41)
MERCAPTOPURINE (40)
DAUNORUBICIN (38)
Which PEMBROLIZUMAB Alternatives Have Lower Central hypothyroidism Risk?
PEMBROLIZUMAB vs PEMETREXED
PEMBROLIZUMAB vs PEMIGATINIB
PEMBROLIZUMAB vs PENICILLAMINE
PEMBROLIZUMAB vs PENICILLIN
PEMBROLIZUMAB vs PENICILLIN G