Central hypothyroidism: Which Medications Cause It? (224 Reports Across 37 Drugs)
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Central hypothyroidism has been reported as an adverse event with 37 different drugs in the FDA's FAERS database, with 224 total reports. 2 of these reports resulted in death.The drugs most commonly associated with Central hypothyroidism are DOXORUBICIN, CYCLOPHOSPHAMIDE, and VINCRISTINE.
224
Total Reports
37
Drugs Involved
2
Deaths
48
Hospitalizations
41.0 yrs
Average Patient Age
62.6% / 37.4%
Female / Male
Which Drugs Cause Central hypothyroidism Most Often?
| Drug | Reports | % of Drug Reports | Deaths | Hosp. | Life-Threat. |
|---|---|---|---|---|---|
| DOXORUBICIN | 77 | 0.1% | 0 | 1 | 0 |
| CYCLOPHOSPHAMIDE | 75 | 0.1% | 0 | 1 | 0 |
| VINCRISTINE | 72 | 0.1% | 0 | 0 | 0 |
| CYTARABINE | 54 | 0.1% | 0 | 0 | 0 |
| PREDNISOLONE | 47 | 0.1% | 0 | 0 | 0 |
| METHOTREXATE | 44 | 0.0% | 0 | 0 | 0 |
| ASPARAGINASE | 42 | 0.8% | 0 | 0 | 0 |
| DEXAMETHASONE | 41 | 0.0% | 0 | 0 | 0 |
| MERCAPTOPURINE | 40 | 0.4% | 0 | 0 | 0 |
| DAUNORUBICIN | 38 | 0.4% | 0 | 0 | 0 |
| CARBOPLATIN | 29 | 0.0% | 0 | 0 | 0 |
| ETOPOSIDE | 28 | 0.1% | 0 | 0 | 0 |
| THIOGUANINE ANHYDROUS | 24 | 2.1% | 0 | 0 | 0 |
| CISPLATIN | 23 | 0.1% | 0 | 0 | 0 |
| MELPHALAN | 23 | 0.1% | 0 | 0 | 0 |
| NIVOLUMAB | 22 | 0.0% | 1 | 14 | 1 |
| IPILIMUMAB | 21 | 0.1% | 1 | 13 | 1 |
| QUETIAPINE | 21 | 0.0% | 0 | 2 | 0 |
| DACTINOMYCIN | 17 | 0.6% | 0 | 0 | 0 |
| FLUDARABINE | 17 | 0.1% | 0 | 0 | 0 |