Does PEMBROLIZUMAB Cause Encephalitis? 352 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 352 reports of Encephalitis have been filed in association with PEMBROLIZUMAB (KEYTRUDA). This represents 0.4% of all adverse event reports for PEMBROLIZUMAB.
352
Reports of Encephalitis with PEMBROLIZUMAB
0.4%
of all PEMBROLIZUMAB reports
90
Deaths
245
Hospitalizations
How Dangerous Is Encephalitis From PEMBROLIZUMAB?
Of the 352 reports, 90 (25.6%) resulted in death, 245 (69.6%) required hospitalization, and 83 (23.6%) were considered life-threatening.
Is Encephalitis Listed in the Official Label?
Yes, Encephalitis is listed as a known adverse reaction in the official FDA drug label for PEMBROLIZUMAB.
What Other Side Effects Does PEMBROLIZUMAB Cause?
Malignant neoplasm progression (10,111)
Death (4,744)
Diarrhoea (4,251)
Fatigue (3,833)
Off label use (3,416)
Product use in unapproved indication (3,191)
Pyrexia (3,155)
Rash (2,900)
Nausea (2,670)
Decreased appetite (2,486)
What Other Drugs Cause Encephalitis?
NIVOLUMAB (377)
METHOTREXATE (372)
PREDNISONE (365)
RITUXIMAB (263)
TACROLIMUS (253)
CYCLOPHOSPHAMIDE (244)
ATEZOLIZUMAB (236)
MYCOPHENOLATE MOFETIL (228)
PREDNISOLONE (190)
DEXAMETHASONE (187)
Which PEMBROLIZUMAB Alternatives Have Lower Encephalitis Risk?
PEMBROLIZUMAB vs PEMETREXED
PEMBROLIZUMAB vs PEMIGATINIB
PEMBROLIZUMAB vs PENICILLAMINE
PEMBROLIZUMAB vs PENICILLIN
PEMBROLIZUMAB vs PENICILLIN G