Does METHOTREXATE Cause Encephalitis? 372 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 372 reports of Encephalitis have been filed in association with METHOTREXATE (Methotrexate). This represents 0.2% of all adverse event reports for METHOTREXATE.
372
Reports of Encephalitis with METHOTREXATE
0.2%
of all METHOTREXATE reports
85
Deaths
181
Hospitalizations
How Dangerous Is Encephalitis From METHOTREXATE?
Of the 372 reports, 85 (22.8%) resulted in death, 181 (48.7%) required hospitalization, and 29 (7.8%) were considered life-threatening.
Is Encephalitis Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for METHOTREXATE. However, 372 reports have been filed with the FAERS database.
What Other Side Effects Does METHOTREXATE Cause?
Drug ineffective (70,142)
Rheumatoid arthritis (29,254)
Off label use (24,020)
Pain (23,773)
Drug intolerance (22,555)
Arthralgia (21,831)
Fatigue (19,885)
Nausea (18,715)
Joint swelling (17,657)
Drug hypersensitivity (16,677)
What Other Drugs Cause Encephalitis?
NIVOLUMAB (377)
PREDNISONE (365)
PEMBROLIZUMAB (352)
RITUXIMAB (263)
TACROLIMUS (253)
CYCLOPHOSPHAMIDE (244)
ATEZOLIZUMAB (236)
MYCOPHENOLATE MOFETIL (228)
PREDNISOLONE (190)
DEXAMETHASONE (187)
Which METHOTREXATE Alternatives Have Lower Encephalitis Risk?
METHOTREXATE vs METHOXSALEN
METHOTREXATE vs METHOXY POLYETHYLENE GLYCOL-EPOETIN BETA
METHOTREXATE vs METHYL ALCOHOL
METHOTREXATE vs METHYLCOBALAMIN
METHOTREXATE vs METHYLDOPA