Does PEMBROLIZUMAB Cause Gastric perforation? 46 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 46 reports of Gastric perforation have been filed in association with PEMBROLIZUMAB (KEYTRUDA). This represents 0.1% of all adverse event reports for PEMBROLIZUMAB.
46
Reports of Gastric perforation with PEMBROLIZUMAB
0.1%
of all PEMBROLIZUMAB reports
15
Deaths
26
Hospitalizations
How Dangerous Is Gastric perforation From PEMBROLIZUMAB?
Of the 46 reports, 15 (32.6%) resulted in death, 26 (56.5%) required hospitalization, and 9 (19.6%) were considered life-threatening.
Is Gastric perforation Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for PEMBROLIZUMAB. However, 46 reports have been filed with the FAERS database.
What Other Side Effects Does PEMBROLIZUMAB Cause?
Malignant neoplasm progression (10,111)
Death (4,744)
Diarrhoea (4,251)
Fatigue (3,833)
Off label use (3,416)
Product use in unapproved indication (3,191)
Pyrexia (3,155)
Rash (2,900)
Nausea (2,670)
Decreased appetite (2,486)
What Other Drugs Cause Gastric perforation?
IBUPROFEN (113)
BEVACIZUMAB (110)
ADALIMUMAB (97)
CARBIDOPA\LEVODOPA (81)
PREDNISONE (70)
CISPLATIN (68)
OXALIPLATIN (68)
DEXAMETHASONE (66)
CAPECITABINE (64)
RITUXIMAB (59)
Which PEMBROLIZUMAB Alternatives Have Lower Gastric perforation Risk?
PEMBROLIZUMAB vs PEMETREXED
PEMBROLIZUMAB vs PEMIGATINIB
PEMBROLIZUMAB vs PENICILLAMINE
PEMBROLIZUMAB vs PENICILLIN
PEMBROLIZUMAB vs PENICILLIN G