Does PEMBROLIZUMAB Cause Hyponatraemia? 629 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 629 reports of Hyponatraemia have been filed in association with PEMBROLIZUMAB (KEYTRUDA). This represents 0.8% of all adverse event reports for PEMBROLIZUMAB.
629
Reports of Hyponatraemia with PEMBROLIZUMAB
0.8%
of all PEMBROLIZUMAB reports
106
Deaths
462
Hospitalizations
How Dangerous Is Hyponatraemia From PEMBROLIZUMAB?
Of the 629 reports, 106 (16.9%) resulted in death, 462 (73.4%) required hospitalization, and 55 (8.7%) were considered life-threatening.
Is Hyponatraemia Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for PEMBROLIZUMAB. However, 629 reports have been filed with the FAERS database.
What Other Side Effects Does PEMBROLIZUMAB Cause?
Malignant neoplasm progression (10,111)
Death (4,744)
Diarrhoea (4,251)
Fatigue (3,833)
Off label use (3,416)
Product use in unapproved indication (3,191)
Pyrexia (3,155)
Rash (2,900)
Nausea (2,670)
Decreased appetite (2,486)
What Other Drugs Cause Hyponatraemia?
FUROSEMIDE (3,127)
HYDROCHLOROTHIAZIDE (2,138)
OMEPRAZOLE (1,635)
LANSOPRAZOLE (1,416)
SERTRALINE (1,332)
RAMIPRIL (1,178)
SPIRONOLACTONE (1,166)
PANTOPRAZOLE (1,134)
INDAPAMIDE (976)
AMLODIPINE (879)
Which PEMBROLIZUMAB Alternatives Have Lower Hyponatraemia Risk?
PEMBROLIZUMAB vs PEMETREXED
PEMBROLIZUMAB vs PEMIGATINIB
PEMBROLIZUMAB vs PENICILLAMINE
PEMBROLIZUMAB vs PENICILLIN
PEMBROLIZUMAB vs PENICILLIN G