Does PEMBROLIZUMAB Cause Left ventricular dysfunction? 47 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 47 reports of Left ventricular dysfunction have been filed in association with PEMBROLIZUMAB (KEYTRUDA). This represents 0.1% of all adverse event reports for PEMBROLIZUMAB.
47
Reports of Left ventricular dysfunction with PEMBROLIZUMAB
0.1%
of all PEMBROLIZUMAB reports
9
Deaths
27
Hospitalizations
How Dangerous Is Left ventricular dysfunction From PEMBROLIZUMAB?
Of the 47 reports, 9 (19.1%) resulted in death, 27 (57.4%) required hospitalization, and 13 (27.7%) were considered life-threatening.
Is Left ventricular dysfunction Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for PEMBROLIZUMAB. However, 47 reports have been filed with the FAERS database.
What Other Side Effects Does PEMBROLIZUMAB Cause?
Malignant neoplasm progression (10,111)
Death (4,744)
Diarrhoea (4,251)
Fatigue (3,833)
Off label use (3,416)
Product use in unapproved indication (3,191)
Pyrexia (3,155)
Rash (2,900)
Nausea (2,670)
Decreased appetite (2,486)
What Other Drugs Cause Left ventricular dysfunction?
DOXORUBICIN (430)
CYCLOPHOSPHAMIDE (426)
TRASTUZUMAB (401)
CLOZAPINE (231)
SACUBITRIL\VALSARTAN (231)
BISOPROLOL (225)
PERTUZUMAB (207)
RITUXIMAB (202)
DOCETAXEL (199)
VINCRISTINE (193)
Which PEMBROLIZUMAB Alternatives Have Lower Left ventricular dysfunction Risk?
PEMBROLIZUMAB vs PEMETREXED
PEMBROLIZUMAB vs PEMIGATINIB
PEMBROLIZUMAB vs PENICILLAMINE
PEMBROLIZUMAB vs PENICILLIN
PEMBROLIZUMAB vs PENICILLIN G