Does PEMBROLIZUMAB Cause Meningitis? 130 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 130 reports of Meningitis have been filed in association with PEMBROLIZUMAB (KEYTRUDA). This represents 0.2% of all adverse event reports for PEMBROLIZUMAB.
130
Reports of Meningitis with PEMBROLIZUMAB
0.2%
of all PEMBROLIZUMAB reports
22
Deaths
84
Hospitalizations
How Dangerous Is Meningitis From PEMBROLIZUMAB?
Of the 130 reports, 22 (16.9%) resulted in death, 84 (64.6%) required hospitalization, and 18 (13.8%) were considered life-threatening.
Is Meningitis Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for PEMBROLIZUMAB. However, 130 reports have been filed with the FAERS database.
What Other Side Effects Does PEMBROLIZUMAB Cause?
Malignant neoplasm progression (10,111)
Death (4,744)
Diarrhoea (4,251)
Fatigue (3,833)
Off label use (3,416)
Product use in unapproved indication (3,191)
Pyrexia (3,155)
Rash (2,900)
Nausea (2,670)
Decreased appetite (2,486)
What Other Drugs Cause Meningitis?
ADALIMUMAB (230)
METHOTREXATE (223)
HUMAN IMMUNOGLOBULIN G (203)
PREDNISONE (171)
RITUXIMAB (156)
ETANERCEPT (145)
NIVOLUMAB (133)
CYCLOPHOSPHAMIDE (122)
INFLIXIMAB (110)
DEXAMETHASONE (108)
Which PEMBROLIZUMAB Alternatives Have Lower Meningitis Risk?
PEMBROLIZUMAB vs PEMETREXED
PEMBROLIZUMAB vs PEMIGATINIB
PEMBROLIZUMAB vs PENICILLAMINE
PEMBROLIZUMAB vs PENICILLIN
PEMBROLIZUMAB vs PENICILLIN G