Does METHOTREXATE Cause Meningitis? 223 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 223 reports of Meningitis have been filed in association with METHOTREXATE (Methotrexate). This represents 0.1% of all adverse event reports for METHOTREXATE.
223
Reports of Meningitis with METHOTREXATE
0.1%
of all METHOTREXATE reports
28
Deaths
119
Hospitalizations
How Dangerous Is Meningitis From METHOTREXATE?
Of the 223 reports, 28 (12.6%) resulted in death, 119 (53.4%) required hospitalization, and 44 (19.7%) were considered life-threatening.
Is Meningitis Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for METHOTREXATE. However, 223 reports have been filed with the FAERS database.
What Other Side Effects Does METHOTREXATE Cause?
Drug ineffective (70,142)
Rheumatoid arthritis (29,254)
Off label use (24,020)
Pain (23,773)
Drug intolerance (22,555)
Arthralgia (21,831)
Fatigue (19,885)
Nausea (18,715)
Joint swelling (17,657)
Drug hypersensitivity (16,677)
What Other Drugs Cause Meningitis?
ADALIMUMAB (230)
HUMAN IMMUNOGLOBULIN G (203)
PREDNISONE (171)
RITUXIMAB (156)
ETANERCEPT (145)
NIVOLUMAB (133)
PEMBROLIZUMAB (130)
CYCLOPHOSPHAMIDE (122)
INFLIXIMAB (110)
DEXAMETHASONE (108)
Which METHOTREXATE Alternatives Have Lower Meningitis Risk?
METHOTREXATE vs METHOXSALEN
METHOTREXATE vs METHOXY POLYETHYLENE GLYCOL-EPOETIN BETA
METHOTREXATE vs METHYL ALCOHOL
METHOTREXATE vs METHYLCOBALAMIN
METHOTREXATE vs METHYLDOPA