Does PEMBROLIZUMAB Cause Pancytopenia? 1,015 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 1,015 reports of Pancytopenia have been filed in association with PEMBROLIZUMAB (KEYTRUDA). This represents 1.2% of all adverse event reports for PEMBROLIZUMAB.
1,015
Reports of Pancytopenia with PEMBROLIZUMAB
1.2%
of all PEMBROLIZUMAB reports
190
Deaths
697
Hospitalizations
How Dangerous Is Pancytopenia From PEMBROLIZUMAB?
Of the 1,015 reports, 190 (18.7%) resulted in death, 697 (68.7%) required hospitalization, and 117 (11.5%) were considered life-threatening.
Is Pancytopenia Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for PEMBROLIZUMAB. However, 1,015 reports have been filed with the FAERS database.
What Other Side Effects Does PEMBROLIZUMAB Cause?
Malignant neoplasm progression (10,111)
Death (4,744)
Diarrhoea (4,251)
Fatigue (3,833)
Off label use (3,416)
Product use in unapproved indication (3,191)
Pyrexia (3,155)
Rash (2,900)
Nausea (2,670)
Decreased appetite (2,486)
What Other Drugs Cause Pancytopenia?
METHOTREXATE (5,377)
CYCLOPHOSPHAMIDE (3,351)
CARBOPLATIN (2,910)
RITUXIMAB (2,400)
LENALIDOMIDE (2,259)
DOXORUBICIN (2,212)
VINCRISTINE (2,180)
ETOPOSIDE (2,129)
DEXAMETHASONE (2,053)
PREDNISONE (1,743)
Which PEMBROLIZUMAB Alternatives Have Lower Pancytopenia Risk?
PEMBROLIZUMAB vs PEMETREXED
PEMBROLIZUMAB vs PEMIGATINIB
PEMBROLIZUMAB vs PENICILLAMINE
PEMBROLIZUMAB vs PENICILLIN
PEMBROLIZUMAB vs PENICILLIN G