Does PEMBROLIZUMAB Cause Pneumatosis intestinalis? 42 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 42 reports of Pneumatosis intestinalis have been filed in association with PEMBROLIZUMAB (KEYTRUDA). This represents 0.1% of all adverse event reports for PEMBROLIZUMAB.
42
Reports of Pneumatosis intestinalis with PEMBROLIZUMAB
0.1%
of all PEMBROLIZUMAB reports
7
Deaths
30
Hospitalizations
How Dangerous Is Pneumatosis intestinalis From PEMBROLIZUMAB?
Of the 42 reports, 7 (16.7%) resulted in death, 30 (71.4%) required hospitalization, and 3 (7.1%) were considered life-threatening.
Is Pneumatosis intestinalis Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for PEMBROLIZUMAB. However, 42 reports have been filed with the FAERS database.
What Other Side Effects Does PEMBROLIZUMAB Cause?
Malignant neoplasm progression (10,111)
Death (4,744)
Diarrhoea (4,251)
Fatigue (3,833)
Off label use (3,416)
Product use in unapproved indication (3,191)
Pyrexia (3,155)
Rash (2,900)
Nausea (2,670)
Decreased appetite (2,486)
What Other Drugs Cause Pneumatosis intestinalis?
METHYLPREDNISOLONE (358)
TACROLIMUS (293)
CYCLOPHOSPHAMIDE (263)
PREDNISONE (258)
MYCOPHENOLATE MOFETIL (235)
DEXAMETHASONE (227)
METHOTREXATE (221)
VINCRISTINE (220)
PREDNISOLONE (213)
ETOPOSIDE (175)
Which PEMBROLIZUMAB Alternatives Have Lower Pneumatosis intestinalis Risk?
PEMBROLIZUMAB vs PEMETREXED
PEMBROLIZUMAB vs PEMIGATINIB
PEMBROLIZUMAB vs PENICILLAMINE
PEMBROLIZUMAB vs PENICILLIN
PEMBROLIZUMAB vs PENICILLIN G