Pneumatosis intestinalis: Which Medications Cause It? (2,141 Reports Across 152 Drugs)
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Pneumatosis intestinalis has been reported as an adverse event with 152 different drugs in the FDA's FAERS database, with 2,141 total reports. 422 of these reports resulted in death.The drugs most commonly associated with Pneumatosis intestinalis are METHYLPREDNISOLONE, TACROLIMUS, and CYCLOPHOSPHAMIDE.
2,141
Total Reports
152
Drugs Involved
422
Deaths
1,128
Hospitalizations
50.2 yrs
Average Patient Age
40.6% / 59.4%
Female / Male
Which Drugs Cause Pneumatosis intestinalis Most Often?
| Drug | Reports | % of Drug Reports | Deaths | Hosp. | Life-Threat. |
|---|---|---|---|---|---|
| METHYLPREDNISOLONE | 358 | 0.6% | 163 | 138 | 42 |
| TACROLIMUS | 293 | 0.3% | 33 | 180 | 44 |
| CYCLOPHOSPHAMIDE | 263 | 0.2% | 151 | 70 | 30 |
| PREDNISONE | 258 | 0.2% | 153 | 74 | 31 |
| MYCOPHENOLATE MOFETIL | 235 | 0.3% | 28 | 154 | 31 |
| DEXAMETHASONE | 227 | 0.2% | 152 | 61 | 20 |
| METHOTREXATE | 221 | 0.1% | 151 | 51 | 11 |
| VINCRISTINE | 220 | 0.3% | 147 | 54 | 12 |
| PREDNISOLONE | 213 | 0.3% | 16 | 142 | 25 |
| ETOPOSIDE | 175 | 0.3% | 149 | 19 | 5 |
| CYTARABINE | 168 | 0.4% | 143 | 16 | 11 |
| DAUNORUBICIN | 154 | 1.6% | 141 | 12 | 8 |
| LEUCOVORIN | 146 | 0.6% | 104 | 21 | 14 |
| MERCAPTOPURINE | 141 | 1.2% | 134 | 6 | 0 |
| PEGASPARGASE | 141 | 1.2% | 133 | 9 | 1 |
| HYDROCORTISONE | 138 | 0.6% | 121 | 11 | 7 |
| ASPARAGINASE | 137 | 2.8% | 126 | 8 | 0 |
| FLUOROURACIL | 131 | 0.3% | 22 | 43 | 19 |
| FILGRASTIM | 127 | 0.9% | 125 | 1 | 0 |
| CYCLOSPORINE | 109 | 0.2% | 47 | 45 | 19 |