Does PEGASPARGASE Cause Pneumatosis intestinalis? 141 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 141 reports of Pneumatosis intestinalis have been filed in association with PEGASPARGASE (ONCASPAR). This represents 1.2% of all adverse event reports for PEGASPARGASE.
141
Reports of Pneumatosis intestinalis with PEGASPARGASE
1.2%
of all PEGASPARGASE reports
133
Deaths
9
Hospitalizations
How Dangerous Is Pneumatosis intestinalis From PEGASPARGASE?
Of the 141 reports, 133 (94.3%) resulted in death, 9 (6.4%) required hospitalization, and 1 (0.7%) were considered life-threatening.
Is Pneumatosis intestinalis Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for PEGASPARGASE. However, 141 reports have been filed with the FAERS database.
What Other Side Effects Does PEGASPARGASE Cause?
Febrile neutropenia (1,589)
Pyrexia (706)
Febrile bone marrow aplasia (668)
Sepsis (548)
Vomiting (530)
Neutropenia (521)
Abdominal pain (469)
Hypertriglyceridaemia (399)
Hypotension (388)
Thrombocytopenia (382)
What Other Drugs Cause Pneumatosis intestinalis?
METHYLPREDNISOLONE (358)
TACROLIMUS (293)
CYCLOPHOSPHAMIDE (263)
PREDNISONE (258)
MYCOPHENOLATE MOFETIL (235)
DEXAMETHASONE (227)
METHOTREXATE (221)
VINCRISTINE (220)
PREDNISOLONE (213)
ETOPOSIDE (175)
Which PEGASPARGASE Alternatives Have Lower Pneumatosis intestinalis Risk?
PEGASPARGASE vs PEGASYS
PEGASPARGASE vs PEGCETACOPLAN
PEGASPARGASE vs PEGFILGRASTIM
PEGASPARGASE vs PEGFILGRASTIM-APGF
PEGASPARGASE vs PEGFILGRASTIM-BMEZ