Does PEMBROLIZUMAB Cause Thyrotoxic crisis? 44 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 44 reports of Thyrotoxic crisis have been filed in association with PEMBROLIZUMAB (KEYTRUDA). This represents 0.1% of all adverse event reports for PEMBROLIZUMAB.
44
Reports of Thyrotoxic crisis with PEMBROLIZUMAB
0.1%
of all PEMBROLIZUMAB reports
4
Deaths
38
Hospitalizations
How Dangerous Is Thyrotoxic crisis From PEMBROLIZUMAB?
Of the 44 reports, 4 (9.1%) resulted in death, 38 (86.4%) required hospitalization, and 12 (27.3%) were considered life-threatening.
Is Thyrotoxic crisis Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for PEMBROLIZUMAB. However, 44 reports have been filed with the FAERS database.
What Other Side Effects Does PEMBROLIZUMAB Cause?
Malignant neoplasm progression (10,111)
Death (4,744)
Diarrhoea (4,251)
Fatigue (3,833)
Off label use (3,416)
Product use in unapproved indication (3,191)
Pyrexia (3,155)
Rash (2,900)
Nausea (2,670)
Decreased appetite (2,486)
What Other Drugs Cause Thyrotoxic crisis?
AMIODARONE (180)
LEVOTHYROXINE (142)
METHIMAZOLE (75)
IPILIMUMAB (36)
NIVOLUMAB (36)
PROPRANOLOL (33)
PROPYLTHIOURACIL (26)
LITHIUM (23)
LENVATINIB (22)
HYDROCORTISONE (19)
Which PEMBROLIZUMAB Alternatives Have Lower Thyrotoxic crisis Risk?
PEMBROLIZUMAB vs PEMETREXED
PEMBROLIZUMAB vs PEMIGATINIB
PEMBROLIZUMAB vs PENICILLAMINE
PEMBROLIZUMAB vs PENICILLIN
PEMBROLIZUMAB vs PENICILLIN G