Does PEMBROLIZUMAB Cause Toxic epidermal necrolysis? 444 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 444 reports of Toxic epidermal necrolysis have been filed in association with PEMBROLIZUMAB (KEYTRUDA). This represents 0.5% of all adverse event reports for PEMBROLIZUMAB.
444
Reports of Toxic epidermal necrolysis with PEMBROLIZUMAB
0.5%
of all PEMBROLIZUMAB reports
211
Deaths
309
Hospitalizations
How Dangerous Is Toxic epidermal necrolysis From PEMBROLIZUMAB?
Of the 444 reports, 211 (47.5%) resulted in death, 309 (69.6%) required hospitalization, and 118 (26.6%) were considered life-threatening.
Is Toxic epidermal necrolysis Listed in the Official Label?
Yes, Toxic epidermal necrolysis is listed as a known adverse reaction in the official FDA drug label for PEMBROLIZUMAB.
What Other Side Effects Does PEMBROLIZUMAB Cause?
Malignant neoplasm progression (10,111)
Death (4,744)
Diarrhoea (4,251)
Fatigue (3,833)
Off label use (3,416)
Product use in unapproved indication (3,191)
Pyrexia (3,155)
Rash (2,900)
Nausea (2,670)
Decreased appetite (2,486)
What Other Drugs Cause Toxic epidermal necrolysis?
ACETAMINOPHEN (980)
LAMOTRIGINE (941)
ALLOPURINOL (858)
IBUPROFEN (764)
SULFAMETHOXAZOLE\TRIMETHOPRIM (592)
CIPROFLOXACIN (576)
FUROSEMIDE (521)
VANCOMYCIN (515)
PIPERACILLIN\TAZOBACTAM (490)
PANTOPRAZOLE (401)
Which PEMBROLIZUMAB Alternatives Have Lower Toxic epidermal necrolysis Risk?
PEMBROLIZUMAB vs PEMETREXED
PEMBROLIZUMAB vs PEMIGATINIB
PEMBROLIZUMAB vs PENICILLAMINE
PEMBROLIZUMAB vs PENICILLIN
PEMBROLIZUMAB vs PENICILLIN G