Does PEMETREXED Cause Myocarditis? 122 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 122 reports of Myocarditis have been filed in association with PEMETREXED (Pemetrexed). This represents 0.5% of all adverse event reports for PEMETREXED.
122
Reports of Myocarditis with PEMETREXED
0.5%
of all PEMETREXED reports
39
Deaths
49
Hospitalizations
How Dangerous Is Myocarditis From PEMETREXED?
Of the 122 reports, 39 (32.0%) resulted in death, 49 (40.2%) required hospitalization, and 34 (27.9%) were considered life-threatening.
Is Myocarditis Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for PEMETREXED. However, 122 reports have been filed with the FAERS database.
What Other Side Effects Does PEMETREXED Cause?
Malignant neoplasm progression (2,149)
Off label use (1,663)
Anaemia (1,430)
Pancytopenia (1,236)
Neutropenia (1,200)
Nausea (1,195)
Diarrhoea (1,165)
Acute kidney injury (1,105)
Thrombocytopenia (1,059)
Disease progression (969)
What Other Drugs Cause Myocarditis?
CLOZAPINE (1,702)
PEMBROLIZUMAB (1,060)
NIVOLUMAB (959)
IPILIMUMAB (475)
OLANZAPINE (425)
ATEZOLIZUMAB (372)
CARBOPLATIN (325)
QUETIAPINE (315)
MESALAMINE (272)
BEVACIZUMAB (230)
Which PEMETREXED Alternatives Have Lower Myocarditis Risk?
PEMETREXED vs PEMIGATINIB
PEMETREXED vs PENICILLAMINE
PEMETREXED vs PENICILLIN
PEMETREXED vs PENICILLIN G
PEMETREXED vs PENICILLIN G BENZATHINE