PEMIGATINIB for Cholangiocarcinoma: Side Effects & Safety Data
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There are 431 adverse event reports in the FDA FAERS database where PEMIGATINIB was used for Cholangiocarcinoma.
Most Reported Side Effects for PEMIGATINIB
| Side Effect | Reports | % | Deaths | Hosp. |
|---|---|---|---|---|
| Off label use | 114 | 16.1% | 28 | 19 |
| Disease progression | 103 | 14.5% | 38 | 13 |
| Death | 76 | 10.7% | 76 | 6 |
| Fatigue | 72 | 10.2% | 5 | 7 |
| Alopecia | 53 | 7.5% | 2 | 5 |
| Hyperphosphataemia | 46 | 6.5% | 10 | 11 |
| Cholangiocarcinoma | 44 | 6.2% | 19 | 4 |
| Diarrhoea | 42 | 5.9% | 0 | 10 |
| Constipation | 37 | 5.2% | 2 | 4 |
| Drug ineffective | 37 | 5.2% | 13 | 3 |
| Hospitalisation | 35 | 4.9% | 0 | 34 |
| Nausea | 35 | 4.9% | 5 | 5 |
| Decreased appetite | 34 | 4.8% | 3 | 5 |
| Stomatitis | 31 | 4.4% | 2 | 6 |
| Dry mouth | 30 | 4.2% | 1 | 2 |
Other Indications for PEMIGATINIB
Bile duct cancer (34)
Glioblastoma (12)
Adenocarcinoma of salivary gland (10)
Pancreatic carcinoma (8)
Malignant lymphoid neoplasm (7)
Bladder cancer (6)
Hepatic cancer (5)
Myeloproliferative neoplasm (5)
Neoplasm malignant (5)
Other Drugs Used for Cholangiocarcinoma
GEMCITABINE (1,181)
CISPLATIN (923)
CAPECITABINE (608)
DURVALUMAB (444)
OXALIPLATIN (441)
FLUOROURACIL (341)
GEMCITABINE\GEMCITABINE (292)
IVOSIDENIB (277)
NIVOLUMAB (250)
IRINOTECAN (231)