PEMIGATINIB for Glioblastoma: Side Effects & Safety Data
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There are 12 adverse event reports in the FDA FAERS database where PEMIGATINIB was used for Glioblastoma.
Most Reported Side Effects for PEMIGATINIB
| Side Effect | Reports | % | Deaths | Hosp. |
|---|---|---|---|---|
| Off label use | 114 | 16.1% | 28 | 19 |
| Disease progression | 103 | 14.5% | 38 | 13 |
| Death | 76 | 10.7% | 76 | 6 |
| Fatigue | 72 | 10.2% | 5 | 7 |
| Alopecia | 53 | 7.5% | 2 | 5 |
| Hyperphosphataemia | 46 | 6.5% | 10 | 11 |
| Cholangiocarcinoma | 44 | 6.2% | 19 | 4 |
| Diarrhoea | 42 | 5.9% | 0 | 10 |
| Constipation | 37 | 5.2% | 2 | 4 |
| Drug ineffective | 37 | 5.2% | 13 | 3 |
| Hospitalisation | 35 | 4.9% | 0 | 34 |
| Nausea | 35 | 4.9% | 5 | 5 |
| Decreased appetite | 34 | 4.8% | 3 | 5 |
| Stomatitis | 31 | 4.4% | 2 | 6 |
| Dry mouth | 30 | 4.2% | 1 | 2 |
Other Indications for PEMIGATINIB
Cholangiocarcinoma (431)
Bile duct cancer (34)
Adenocarcinoma of salivary gland (10)
Pancreatic carcinoma (8)
Malignant lymphoid neoplasm (7)
Bladder cancer (6)
Hepatic cancer (5)
Myeloproliferative neoplasm (5)
Neoplasm malignant (5)
Other Drugs Used for Glioblastoma
TEMOZOLOMIDE (2,346)
BEVACIZUMAB (1,610)
NIVOLUMAB (365)
IRINOTECAN (182)
LOMUSTINE (163)
PEMBROLIZUMAB (102)
CARBOPLATIN (97)
AVASTIN (80)
BEVACIZUMAB-AWWB (78)
DEXAMETHASONE (78)