PERTUZUMAB for Off label use: Side Effects & Safety Data
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There are 8 adverse event reports in the FDA FAERS database where PERTUZUMAB was used for Off label use.
Most Reported Side Effects for PERTUZUMAB
| Side Effect | Reports | % | Deaths | Hosp. |
|---|---|---|---|---|
| Diarrhoea | 3,343 | 15.2% | 312 | 1,647 |
| Off label use | 1,886 | 8.6% | 373 | 655 |
| Fatigue | 1,672 | 7.6% | 249 | 799 |
| Nausea | 1,669 | 7.6% | 203 | 858 |
| Myelosuppression | 1,311 | 6.0% | 3 | 637 |
| Disease progression | 1,142 | 5.2% | 401 | 306 |
| Vomiting | 1,096 | 5.0% | 128 | 691 |
| Dyspnoea | 987 | 4.5% | 86 | 565 |
| Neuropathy peripheral | 983 | 4.5% | 161 | 347 |
| Pyrexia | 926 | 4.2% | 86 | 596 |
| Neutropenia | 856 | 3.9% | 165 | 368 |
| Death | 807 | 3.7% | 807 | 78 |
| Rash | 807 | 3.7% | 18 | 198 |
| Alopecia | 801 | 3.6% | 116 | 255 |
| Anaemia | 756 | 3.4% | 52 | 356 |
Other Indications for PERTUZUMAB
Breast cancer (7,532)
Breast cancer metastatic (3,784)
Her2 positive breast cancer (3,037)
Product used for unknown indication (2,659)
Her-2 positive breast cancer (2,005)
Invasive ductal breast carcinoma (633)
Breast cancer female (419)
Invasive breast carcinoma (322)
Neoplasm malignant (217)
Breast cancer stage iv (128)
Other Drugs Used for Off label use
LENALIDOMIDE (5,767)
ECULIZUMAB (3,550)
CERTOLIZUMAB PEGOL (2,256)
ABOBOTULINUMTOXINA (2,170)
LEVETIRACETAM (2,161)
APREMILAST (1,995)
PROPRANOLOL (1,576)
CETIRIZINE (1,416)
HUMAN IMMUNOGLOBULIN G (1,129)
THALIDOMIDE (1,033)