Does PERTUZUMAB Cause Hyponatraemia? 83 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 83 reports of Hyponatraemia have been filed in association with PERTUZUMAB (PERJETA). This represents 0.4% of all adverse event reports for PERTUZUMAB.
83
Reports of Hyponatraemia with PERTUZUMAB
0.4%
of all PERTUZUMAB reports
24
Deaths
70
Hospitalizations
How Dangerous Is Hyponatraemia From PERTUZUMAB?
Of the 83 reports, 24 (28.9%) resulted in death, 70 (84.3%) required hospitalization, and 2 (2.4%) were considered life-threatening.
Is Hyponatraemia Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for PERTUZUMAB. However, 83 reports have been filed with the FAERS database.
What Other Side Effects Does PERTUZUMAB Cause?
Diarrhoea (3,343)
Off label use (1,886)
Fatigue (1,672)
Nausea (1,669)
Myelosuppression (1,311)
Disease progression (1,142)
Vomiting (1,096)
Dyspnoea (987)
Neuropathy peripheral (983)
Pyrexia (926)
What Other Drugs Cause Hyponatraemia?
FUROSEMIDE (3,127)
HYDROCHLOROTHIAZIDE (2,138)
OMEPRAZOLE (1,635)
LANSOPRAZOLE (1,416)
SERTRALINE (1,332)
RAMIPRIL (1,178)
SPIRONOLACTONE (1,166)
PANTOPRAZOLE (1,134)
INDAPAMIDE (976)
AMLODIPINE (879)
Which PERTUZUMAB Alternatives Have Lower Hyponatraemia Risk?
PERTUZUMAB vs PERTUZUMAB\TRASTUZUMAB
PERTUZUMAB vs PETROLATUM
PERTUZUMAB vs PEVONEDISTAT
PERTUZUMAB vs PEXIDARTINIB
PERTUZUMAB vs PHENACETIN