Does PERTUZUMAB Cause Osteosclerosis? 29 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 29 reports of Osteosclerosis have been filed in association with PERTUZUMAB (PERJETA). This represents 0.1% of all adverse event reports for PERTUZUMAB.
29
Reports of Osteosclerosis with PERTUZUMAB
0.1%
of all PERTUZUMAB reports
5
Deaths
3
Hospitalizations
How Dangerous Is Osteosclerosis From PERTUZUMAB?
Of the 29 reports, 5 (17.2%) resulted in death, 3 (10.3%) required hospitalization.
Is Osteosclerosis Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for PERTUZUMAB. However, 29 reports have been filed with the FAERS database.
What Other Side Effects Does PERTUZUMAB Cause?
Diarrhoea (3,343)
Off label use (1,886)
Fatigue (1,672)
Nausea (1,669)
Myelosuppression (1,311)
Disease progression (1,142)
Vomiting (1,096)
Dyspnoea (987)
Neuropathy peripheral (983)
Pyrexia (926)
What Other Drugs Cause Osteosclerosis?
METHOTREXATE (166)
ETANERCEPT (131)
ZOLEDRONIC ACID (124)
ZOMETA (123)
ABATACEPT (115)
LEFLUNOMIDE (115)
ADALIMUMAB (106)
AREDIA (82)
RITUXIMAB (78)
DENOSUMAB (76)
Which PERTUZUMAB Alternatives Have Lower Osteosclerosis Risk?
PERTUZUMAB vs PERTUZUMAB\TRASTUZUMAB
PERTUZUMAB vs PETROLATUM
PERTUZUMAB vs PEVONEDISTAT
PERTUZUMAB vs PEXIDARTINIB
PERTUZUMAB vs PHENACETIN