Does PERTUZUMAB Cause Pancytopenia? 135 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 135 reports of Pancytopenia have been filed in association with PERTUZUMAB (PERJETA). This represents 0.6% of all adverse event reports for PERTUZUMAB.
135
Reports of Pancytopenia with PERTUZUMAB
0.6%
of all PERTUZUMAB reports
55
Deaths
68
Hospitalizations
How Dangerous Is Pancytopenia From PERTUZUMAB?
Of the 135 reports, 55 (40.7%) resulted in death, 68 (50.4%) required hospitalization, and 3 (2.2%) were considered life-threatening.
Is Pancytopenia Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for PERTUZUMAB. However, 135 reports have been filed with the FAERS database.
What Other Side Effects Does PERTUZUMAB Cause?
Diarrhoea (3,343)
Off label use (1,886)
Fatigue (1,672)
Nausea (1,669)
Myelosuppression (1,311)
Disease progression (1,142)
Vomiting (1,096)
Dyspnoea (987)
Neuropathy peripheral (983)
Pyrexia (926)
What Other Drugs Cause Pancytopenia?
METHOTREXATE (5,377)
CYCLOPHOSPHAMIDE (3,351)
CARBOPLATIN (2,910)
RITUXIMAB (2,400)
LENALIDOMIDE (2,259)
DOXORUBICIN (2,212)
VINCRISTINE (2,180)
ETOPOSIDE (2,129)
DEXAMETHASONE (2,053)
PREDNISONE (1,743)
Which PERTUZUMAB Alternatives Have Lower Pancytopenia Risk?
PERTUZUMAB vs PERTUZUMAB\TRASTUZUMAB
PERTUZUMAB vs PETROLATUM
PERTUZUMAB vs PEVONEDISTAT
PERTUZUMAB vs PEXIDARTINIB
PERTUZUMAB vs PHENACETIN