Does PEVONEDISTAT Cause Hyponatraemia? 6 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 6 reports of Hyponatraemia have been filed in association with PEVONEDISTAT. This represents 1.1% of all adverse event reports for PEVONEDISTAT.
6
Reports of Hyponatraemia with PEVONEDISTAT
1.1%
of all PEVONEDISTAT reports
2
Deaths
4
Hospitalizations
How Dangerous Is Hyponatraemia From PEVONEDISTAT?
Of the 6 reports, 2 (33.3%) resulted in death, 4 (66.7%) required hospitalization, and 2 (33.3%) were considered life-threatening.
Is Hyponatraemia Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for PEVONEDISTAT. However, 6 reports have been filed with the FAERS database.
What Other Side Effects Does PEVONEDISTAT Cause?
Febrile neutropenia (77)
Pneumonia (55)
Pyrexia (34)
Anaemia (33)
Septic shock (33)
Thrombocytopenia (31)
General physical health deterioration (28)
Acute myeloid leukaemia (26)
Sepsis (25)
Nausea (16)
What Other Drugs Cause Hyponatraemia?
FUROSEMIDE (3,127)
HYDROCHLOROTHIAZIDE (2,138)
OMEPRAZOLE (1,635)
LANSOPRAZOLE (1,416)
SERTRALINE (1,332)
RAMIPRIL (1,178)
SPIRONOLACTONE (1,166)
PANTOPRAZOLE (1,134)
INDAPAMIDE (976)
AMLODIPINE (879)
Which PEVONEDISTAT Alternatives Have Lower Hyponatraemia Risk?
PEVONEDISTAT vs PEXIDARTINIB
PEVONEDISTAT vs PHENACETIN
PEVONEDISTAT vs PHENAZOPYRIDINE
PEVONEDISTAT vs PHENCYCLIDINE
PEVONEDISTAT vs PHENELZINE