Does PHENYTOIN Cause Pancytopenia? 45 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 45 reports of Pancytopenia have been filed in association with PHENYTOIN (PHENYTOIN SODIUM). This represents 0.3% of all adverse event reports for PHENYTOIN.
45
Reports of Pancytopenia with PHENYTOIN
0.3%
of all PHENYTOIN reports
7
Deaths
24
Hospitalizations
How Dangerous Is Pancytopenia From PHENYTOIN?
Of the 45 reports, 7 (15.6%) resulted in death, 24 (53.3%) required hospitalization, and 8 (17.8%) were considered life-threatening.
Is Pancytopenia Listed in the Official Label?
Yes, Pancytopenia is listed as a known adverse reaction in the official FDA drug label for PHENYTOIN.
What Other Side Effects Does PHENYTOIN Cause?
Drug ineffective (2,753)
Seizure (1,907)
Toxicity to various agents (1,248)
Drug hypersensitivity (898)
Off label use (852)
Drug interaction (772)
Drug reaction with eosinophilia and systemic symptoms (673)
Status epilepticus (544)
Fall (436)
Rash (414)
What Other Drugs Cause Pancytopenia?
METHOTREXATE (5,377)
CYCLOPHOSPHAMIDE (3,351)
CARBOPLATIN (2,910)
RITUXIMAB (2,400)
LENALIDOMIDE (2,259)
DOXORUBICIN (2,212)
VINCRISTINE (2,180)
ETOPOSIDE (2,129)
DEXAMETHASONE (2,053)
PREDNISONE (1,743)
Which PHENYTOIN Alternatives Have Lower Pancytopenia Risk?
PHENYTOIN vs PHLEUM PRATENSE POLLEN
PHENYTOIN vs PHLOROGLUCINOL
PHENYTOIN vs PHLOROGLUCINOL\1,3,5-TRIMETHOXYBENZENE
PHENYTOIN vs PHOLCODINE
PHENYTOIN vs PHOSPHORUS